Chemical space covered by bitter tastants, food derived compounds and drug compounds

Supplementary figures to Dunkel, Hofmann and Di Pizio (2020): In-silico investigation of bitter hop-derived compounds and their cognate bitter taste receptors

Chemical space of bitter tastants

t-SNE plot of the bitter chemical space, coloured according FooDB and DrugBank co-occurrence

t-SNE plot of the bitter chemical space, coloured according to ClassyFire chemical superclasses

t-SNE plot of the bitter (in yellow) chemical space, hop-derived compounds 1-11 are coloured in black

Chemical space of FooDB, BitterDB and DrugBank

t-SNE plot of FooDB, BitterDB and DrugBank, coloured according to database occurrence

t-SNE plot of FooDB, BitterDB and DrugBank, coloured according to ClassyFire chemical superclasses

t-SNE plot of FooDB, BitterDB and DrugBank highlighting hop-derived compounds 1-11